The Expanding Prevalence of Beta-博彩app软件下载

Countries around the world are preparing for a rise in cases.

December 01, 2018
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eta-博彩app软件下载 is a blood disorder, with more than 60,000 infants born worldwide with the disease each year. However, unless you live in Asia, India, the Middle East or the Mediterranean where beta-博彩app软件下载 is most prevalent, you may never have heard of this inherited blood disorder that disrupts the body’s ability to make hemoglobin. 

But that may be changing as doctors in Europe and North America are increasingly encountering patients with beta-博彩app软件下载. “We’re only now starting to deal with it, and there is a lot of work that needs to be done,” explained Dr. Maria Domenica Cappellini, a hematologist at the University of Milan in Italy, whose research focuses on the disease. 

As hematologists gathered for the 2018 American Society of Hematology Annual Meeting in San Diego, Cappellini and other experts sounded the alarm 博彩app软件下载app软件 the expanding prevalence of beta-博彩app软件下载 so that physicians and health systems everywhere can better prepare for an increasing number of patients with this genetic disorder. 

Spreading Faster Than Ever 

Beta-博彩app软件下载 is an inherited disease caused by mutations in a gene required for making a component of hemoglobin – a protein that carries oxygen in the blood. Those mutations either prevent or reduce the production of hemoglobin, which can cause a shortage of mature red blood cells and lead to anemia. 

Dr. Maria Domenica Cappellini, A Hematologist At The University Of Milan In Italy, Believes More Countries Need To Prepare For The Expanding Prevalence Of Beta-Thalassemia.

Dr. Maria Domenica Cappellini, A Hematologist At The University Of Milan In Italy, Believes More Countries Need To Prepare For The Expanding Prevalence Of Beta-Thalassemia.

Often times, children inherit the gene mutation from parents who are carriers but do not show any symptoms of the disease. In this scenario, the child has a 25 percent chance of developing beta-博彩app软件下载 and a 50 percent chance of being an asymptomatic carrier like their parents. 

The mutations that cause beta-博彩app软件下载 are more common in Asia, India, the Middle East and the Mediterranean where they are found in up to 20 percent of the population. But the increase in modern migration means that cases are now cropping up more often in other regions. 

Southern Mediterranean countries recognize the rise in patients with beta-博彩app软件下载 and have increased resources to meet the growing demand appropriately. While in Northern and Western Europe, health professionals and policymakers acknowledge this trend, they lack reliable data on the frequency and patterns of the disease just yet. Without data, it’s difficult to make the case for investing in programs to address the issue, which means patients struggle to find the right doctors. 

Bracing for Beta-博彩app软件下载 

Many patients with beta-博彩app软件下载 require life-long regular blood transfusions and medication to reduce the levels of iron in their body. “These patients cannot produce enough mature red blood cells to transport oxygen throughout their bodies,” Cappellini said. “So transfusions are necessary for their survival.” 

Understandably, beta-博彩app软件下载 treatment requires significant expertise and resources, including safe blood donations. Many countries are preparing their health care systems by improving resources for blood transfusions. “As migration throughout the world continues to change, health care systems will need to evolve rapidly to meet the needs of a more diverse population,” Cappellini said. 

“I get daily emails from colleagues in other parts of Europe asking how to treat patients with beta-博彩app软件下载,” Cappellini said. “We’re trying to make this information as accessible and comprehensive as possible.” 

Beta-博彩app软件下载 is something that hematologists in North America and Europe need to get up to speed on and quickly. 

Longer Term Solutions 

We’re still a long way from being able to correct or erase the mutation that causes beta-博彩app软件下载. Currently, the only available cure is a stem cell transplant, but many patients may not be eligible. Fewer than 10 percent of patients eligible for a stem cell transplant actually receive one, often due to high costs or a lack of a donor. 

Meanwhile, researchers are constantly looking at other ways to improve treatment options and patients’ quality of life, including therapies that could reduce the need for red blood cell transfusions. Transfusion frequencies vary based on patient needs, sometimes requiring them to spend hours receiving treatment every couple of weeks. 

Another long-term solution is prevention through carrier screening and education, and some countries have found success with this approach. For instance, Cyprus, Italy and Greece enacted mandatory premarital screening and genetic counselling in the 1970s and have subsequently achieved almost a 100 percent reduction in at-risk births. 

Without mandatory screenings, health care systems rely on education to reduce the incidence of beta-博彩app软件下载. “If we don’t educate more populations 博彩app软件下载app软件 how this disease is transmitted, we will continue to see an increasing number of carriers and an expanding prevalence of beta-博彩app软件下载 around the world,” said Cappellini. “Beta-博彩app软件下载 is something that hematologists in North America and Europe need to get up to speed on, and quickly.” 

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